Treatment of type 2 diabetes mellitus, particularly in overweight patients, when dietary management and exercise alone does not result in adequate glycaemic control. In type 1 diabetes, it may be given as an adjuvant to patients whose diabetic are poorly controlled.
In adults, metformin film-coated tablets may be used as monotherapy or in combination with other oral anti-diabetic agents or with insulin.
In children from 10 years of age and adolescents, metformin film-coated tablets may be used as monotherapy or in combination with insulin.
A reduction of diabetic complications has been shown in overweight type 2 diabetic adult patients treated with metformin as first-line therapy after diet failure.